Postfix Flush the Mail Queue

Traditionally you use the "postfix -d ALL" command to flush mail queue under Postfix.

Under Postfix MTA, just enter the following command to flush the mail queue:
# postfix flushOR
# postfix -f

To see mail queue, enter:
# mailq

To remove all mail from the queue, enter:
# postsuper -d ALL

To remove all mails in the deferred queue, enter:
# postsuper -d ALL deferred

postfix-delete.pl script

Following script deletes all mail from the mailq which matches the regular expression specified as the first argument (Credit: ??? - I found it on old good newsgroup)

#!/usr/bin/perl
 
$REGEXP = shift || die "no email-adress given (regexp-style, e.g. bl.*\@yahoo.com)!";
 
@data = qx</usr/sbin/postqueue -p>;
for (@data) {
  if (/^(\w+)(\*|\!)?\s/) {
     $queue_id = $1;
  }
  if($queue_id) {
    if (/$REGEXP/i) {
      $Q{$queue_id} = 1;
      $queue_id = "";
    }
  }
}
 
#open(POSTSUPER,"|cat") || die "couldn't open postsuper" ;
open(POSTSUPER,"|postsuper -d -") || die "couldn't open postsuper" ;
 
foreach (keys %Q) {
  print POSTSUPER "$_\n";
};
close(POSTSUPER);
 

For example, delete all queued messages from or to the domain called fackspamdomain.com, enter:
./postfix-delete.pl fackspamdomain.com
Delete all queued messages that contain the word "xyz" in the e-mail address:
./postfix-delete.pl xyz

Updated for accuracy.

LINK : http://www.cyberciti.biz/tips/howto-postfix-flush-mail-queue.html